Clínic Barcelona. Hospital Universitari
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January 30, 2015

A lipid mediators derived from omega-3 keys to decrease inflammation in the liver by obesity

A study led by Dr. Joan Claria, a researcher from the Physiopathology and treatment of ascites and renal function disorder in liver cirrhosis group of IDIBAPS and consultant of the Department of Biochemistry and Molecular Genetics, CDB, Hospital Clínic, demonstrates for the first time, by inhibiting the enzyme responsible for degrading a lipid mediator derived from omega-3 fatty acids may modulate inflammation associated with liver fat accumulation. In addition, these compounds, called epoxides, the liver cells do capable of removing fat degraded by a process called cell components autophagy. In this study, published in the journal Proceedings of the National Academy of Sciences (PNAS), also involved researchers from the University of California. The first author of the paper is Cristina López-Vicario, predoctoral researcher of the IDIBAPS group.



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