Clínic Barcelona. Hospital Universitari

Rafael Oliva Virgili

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Hospital Clínic – Biomedical Diagnostic CenterBiochemistry and Molecular Genetics

  • Genetics of male infertility. Y chromosome microdeletions Genetic causes of azoospermia or severe oligospermia. DAZ gene.
  • Hereditary hemochromatosis. Genetic causes of iron overload. Mutational study of the HFE gene, ferrroportin, hepcidin and hemojuvelin. Genetic counseling in hemochromatosis.
  • Clinical genetics and genetic counseling. Visit patients in outpatient settings. Diagnosis, prevention and treatment of hereditary diseases. Carrier screening.
  • Other molecular studies: APOE genotyping, mutational study in Alzheimer's disease. Diagnosis of fetal aneuploidies using QF-PCR.
  • Genetics and genomics of male infertility. Mutational studies of candidate genes in male infertility. Y chromosome microdeletions Genomics and massive genomic sequencing.
  • Proteomics of human sperm and male infertility. Characterization of proteins through mass spectrometry. Identification of altered proteins in infertile patients.
  • Epigenetics and epigenomics of spermatozoa. Differential gene distribution regions and nucleoprotamine nucleohistone. Potential epigenetic chromatin proteins of the sperm.
  • Transcriptomics of the germ line, human sperm and male infertility.
  • Medical Genetics. Coordination of Medical Genetics course taught as a core subject in the third year of medicine at the Medical School of the University of Barcelona.
  • Human Genome. Coordination of the optional subject "Human genome research and new developments in diagnosis and treatment", Faculty of Medicine, University of Barcelona.
  • Hematology, Clinical Biochemistry and Genetics. Coordination of the subject "Hematology, Biochemistry and Genetics Clinics" Grade of Biomedical Sciences at the University of Barcelona.
  • Doctoral program. Participant in the doctoral program in Biomedicine and Medicine PhD program.

Other charges

  • Full Professor, Coordinator of Medical Genetics at the Faculty of Medicine of the Universtiy of Barcelona

  • Member of the Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

Recent articles

Academic Qualifications

  • Máster en Gestión Hospitalaria y Servicos Sanitarios (2000)
  • Medical Doctor (1986)
  • PhD (1986)

Biomedical Diagnostic Center (CDB)

Villarroel, 170 · 08036 Barcelona
Tel: +34 93 227 54 64 · Fax: +34 93 227 98 75 · · www.hospitalclinic.org