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C24:0 and C26:0 lysophosphatidylcholines and C22-C26 acylcarnitines, dried blood

Fee code: 16384

Components: C24:0-LPC, C26:0-LPC, (C22) Docosanoylcarnitine, (C24) Tetracosanoylcarnitine, (C26) Hexacosanoylcarnitine and (C24+C26)/C22 ratio

Aliases: C24:0-LPC, C26:0-LPC, VLCFA, LPC, lysoPC, docosanoylcarnitine, tetracosanoylcarnitine, hexacosanoylcarnitine, peroxisomal beta-oxidation deficiencies, X-ALD, Zellweger spectrum disorders

Physician:

Blai Morales Romero

Method description

Liquid ultra chromatography-tandem mass spectrometry (UPLC-MS/MS)

Delivery time

14 days

Note to delivery time

Requisites

Fasting. An attached summary of medical history is required. Date of birth and patient's full name are required.

Specimen type

Dried blood spot

Specimen volume

3 círculos impregnados por ambas caras

Specimen minimum volume

1 círculo impregnado por ambas caras

Collection instructions

Do not use any anticoagulant

Preanalytic treatment

---

Transport conditions

At room temperature

Rejection criteria

Disks not properly impregnated, Sample of oversaturated paper, Insufficient sample, Sample in bad conditions

Results

Reference values

Values Units   Age  
C24:0-LPC 0,17 - 1,00 µmol/L   <= 7 days 
C24:0-LPC 0,17 - 1,00 µmol/L   >7 days to < 1 month  
C24:0-LPC 0,24 - 0,96 µmol/L   1 month to < 1 year 
C24:0-LPC 0,33 - 1,06 µmol/L   1 year to < 8 years 
C24:0-LPC 0,30 - 0,98 µmol/L   >= 8 años 
C26:0-LPC 0,15 - 0,61 µmol/L   <= 7 days 
C26:0-LPC 0,09 - 0,57 µmol/L   >7 days to < 1 month 
C26:0-LPC 0,15 - 0,41 µmol/L   1 month to < 1 year 
C26:0-LPC 0,18 - 0,33 µmol/L   1 year to < 8 years 
C26:0-LPC 0,16 - 0,34 µmol/L   >= 8 years 
(C22) Docosanoylcarnitine 0,00 - 0,05 µmol/L   <= 7 days 
(C22) Docosanoylcarnitine 0,00 - 0,03 µmol/L   >7 days to < 1 month 
(C22) Docosanoylcarnitine 0,00 - 0,01 µmol/L   1 month to < 1 year 
(C22) Docosanoylcarnitine 0,00 - 0,01 µmol/L   1 year to < 8 years 
(C22) Docosanoylcarnitine 0,01 - 0,01 µmol/L   >= 8 years 
(C24) Tetracosanoylcarnitine 0,01 - 0,05 µmol/L   <= 7 days 
(C24) Tetracosanoylcarnitine 0,01 - 0,06 µmol/L   >7 days to < 1 month 
(C24) Tetracosanoylcarnitine 0,01 - 0,03 µmol/L   1 month to < 1 year 
(C24) Tetracosanoylcarnitine 0,01 - 0,02 µmol/L   1 year to < 8 years 
(C24) Tetracosanoylcarnitine 0,01 - 0,02 µmol/L   >= 8 years 
(C26) Hexacosanoylcarnitine 0,01 - 0,05 µmol/L   <= 7 days 
(C26) Hexacosanoylcarnitine 0,01 - 0,04 µmol/L   >7 days to < 1 month 
(C26) Hexacosanoylcarnitine 0,01 - 0,04 µmol/L   1 month to < 1 year  
(C26) Hexacosanoylcarnitine 0,01 - 0,03 µmol/L   1 year to < 8 years 
(C26) Hexacosanoylcarnitine 0,01 - 0,05 µmol/L   >= 8 years 
(C24+C26)/C22 0,0 - 6,0 µmol/L   <= 7 days 
(C24+C26)/C22 0,0 - 6,9 µmol/L   >7 days to < 1 month 
(C24+C26)/C22 0,0 - 7,6 µmol/L   1 month to < 1 year 
(C24+C26)/C22 0,0 - 5,3 µmol/L   1 year to < 8 years 
(C24+C26)/C22 2,0 - 6,8 µmol/L   >= 8 years 

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Biomedical Diagnostic Center (CDB)

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